Praeruptorin A

CAS No. 73069-27-9

Praeruptorin A( —— )

Catalog No. M19050 CAS No. 73069-27-9

Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 116 In Stock
10MG 197 In Stock
25MG 295 In Stock
50MG 446 In Stock
100MG 620 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Praeruptorin A
  • Note
    Research use only, not for human use.
  • Brief Description
    Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.
  • Description
    Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    CAM
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    73069-27-9
  • Formula Weight
    386.4
  • Molecular Formula
    C21H22O7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 33.33 mg/mL (86.26 mM)
  • SMILES
    C/C=C(/C)\C(=O)O[C@H]1[C@H](c2c(ccc3c2oc(=O)cc3)OC1(C)C)OC(=O)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Xu Z1, Wang X, Dai Y, Kong L, et al..Chem Biol Interact. 2010 Jul 30;186(2):239-46.
molnova catalog
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